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Isadora’s current work engages with the concept of novel ecosystems—drawn from the fields of environmental conservation and restoration—as a framework for examining the systems of value that shape our experiences and interactions with the material world. Central to this inquiry is her studio-based sculptural practice, which serves as a point of convergence for exploring material encounters within the local environment, a landscape situated between remnant waterways, heavy industry, and suburban development.

In this context, materials function not merely as passive substances but as carriers of complex political and cultural values. Their presence reveals the limitations of conventional approaches that treat both living and non-living matter as static or predetermined. By considering novel ecosystems as dynamic material assemblages, her work investigates how such entanglements can be spatially articulated through sculpture, offering a means to critically engage with the changing ecologies of the contemporary landscape.

Vaughan has created new commissions for Yield Strength: 2026 Adelaide Biennial of Australian Art, Art Gallery of South Australia and Samstag Museum of Art, Adelaide; The National 2021: New Australian Art, Carriageworks, Sydney; Overlapping Magisteria: The 2020 Macfarlane Commissions, Australian Centre for Contemporary Art, Melbourne; and TarraWarra Biennial 2018: From Will to Form, TarraWarra Museum of Art, Victoria. Vaughan has had significant solo exhibitions at Heide Museum of Modern Art, Melbourne, and Gertrude Glasshouse, Melbourne.